endocarditis
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: flucloxacilline iv loading dose 2g, 12g continuous per 24 hours +
vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours |
Remarks:
Kunstklep; empirische therapie |
|
Medication: amoxicilline iv 2g 6dd +
ceftriaxon iv 2g 2dd |
Remarks:
Natieve klep; subacuut begin; empirische therapie |
|
|
Medication: flucloxacilline iv 2g 6dd or
flucloxacilline iv loading dose 2g, 12g continuous per 24 hours |
Remarks:
Natieve klep; acuut begin; empirische therapie |
| Priority | Medication | Remarks |
|---|---|---|
|
Medication: ceftriaxon iv 2g 1dd +
vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours |
Remarks:
Natieve klep; subacuut begin; empirische therapie |
|
|
Medication: cefazoline iv 2g 3dd or
cefazoline iv loading dose 2g, 6g continuous per 24 hours |
Remarks:
Natieve klep; acuut begin; empirische therapie |
|
|
Medication: cefazoline iv loading dose 2g, 6g continuous per 24 hours +
vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours |
Remarks:
kunstklep; empirische therapie |
| Priority | Medication | Remarks |
|---|---|---|
|
Medication: vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours or
vancomycine iv loading dose 30mg/kg, 17.5mg/kg 2dd |
Remarks:
Natieve klep; acuut begin; empirische therapie |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-501973.4
Updated: 10/09/2025 - 10:08
Status: Published
General comments
vancomycine dosering: oplaaddosis 20 mg/kg, vervolgens 35 mg/kg continu per 24 uur, OF oplaaddosis 30 mg/kg, vervolgens 17,5 mg/kg 2 dd. Onderhoudsdosering vancomycine verder afhankelijk van nierfunctie en van gemeten spiegels, zie bij vancomycine en bij TDM vancomycine
Empirische therapie aanpassen op geleide kweek. zie SWAB richtlijn